BSI PD ISO/TR 19601:2017
$198.66
Nanotechnologies. Aerosol generation for air exposure studies of nano-objects and their aggregates and agglomerates (NOAA)
| Published By | Publication Date | Number of Pages |
| BSI | 2017 | 64 |
PDF Catalog
| PDF Pages | PDF Title |
|---|---|
| 2 | undefined |
| 7 | Foreword |
| 8 | Introduction |
| 9 | 1 Scope 2 Normative references 3 Terms and definitions |
| 15 | 4 Abbreviated terms |
| 16 | 5 Study design considerations 5.1 General 5.2 Workplace exposure scenario |
| 17 | 5.3 Existing inhalation toxicity testing guidelines 5.4 Globally harmonized system of classification and labelling of chemicals (GHS) 6 Considerations in selection of proper generators 6.1 Basic scheme 6.1.1 Flow chart |
| 19 | 6.1.2 Selection of study 6.1.3 Characterization of physicochemical properties of nanomaterials 6.1.4 Exposure information on possible use or handling and manufacturing 6.1.5 Exposure characteristics |
| 20 | 6.1.6 Types of inhalation exposure methods 6.1.7 Particle characterization method 7 NOAA aerosol generators 7.1 General |
| 23 | 7.2 Dry dissemination 7.2.1 Wright dust feeder (see Figure 2) |
| 24 | 7.2.2 Brush type aerosol generator (see Figure 3) |
| 25 | 7.2.3 Small scale powder disperser (SSPD; see Figure 4) |
| 26 | 7.2.4 Fluidized bed aerosol generator (FBG; see Figure 5) |
| 27 | 7.2.5 Acoustic dry aerosol generator elutriator (ADAGE; see Figure 6) |
| 28 | 7.2.6 Vilnius aerosol generator (VAG; see Figure 7) |
| 29 | 7.2.7 Rotating drum generator (see Figure 8) |
| 31 | 7.3 Wet dissemination 7.3.1 Atomizer/nebulizer (see Figure 9 to Figure 11) |
| 34 | 7.3.2 Electro-static assist axial atomizer (see Figure 12) |
| 35 | 7.4 Phase change 7.4.1 Evaporation/condensation generator (see Figure 13) |
| 36 | 7.4.2 Spark generator |
| 37 | 7.4.3 Condensation nano-aerosols |
| 38 | 7.5 Chemical reaction 7.5.1 Combustion |
| 40 | 7.6 Liquid phase filtration/dispersion — Critical point drying (tertiary butyl alcohol sublimation) and direct injection system for whole-body inhalation studies 7.6.1 Principle of operation 7.6.2 Advantages 7.6.3 Limitations |
| 44 | 8 Experimental integration 8.1 General |
| 45 | 8.2 Exposure characterization 8.3 Particle properties 8.4 Considerations for in vivo exposure systems |
| 46 | 9 Considerations in use of nano-aerosol generator for in vitro study |
| 47 | Annex A (informative) NOAA generators, their particle size distribution and measurement methods |
| 52 | Annex B (informative) Aerosol dilution system |
| 55 | Bibliography |
