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ASTM-E2524 2008

$40.63

E2524-08 Standard Test Method for Analysis of Hemolytic Properties of Nanoparticles

Published By Publication Date Number of Pages
ASTM 2008 5
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1.1 This test method covers assessing the effect of nanoparticulate materials on the integrity of red blood cells.

1.2 This test method uses diluted whole blood incubated with nanoparticulate material and the hemoglobin released from damaged red blood cells is determined.

1.3 This test method is similar to Practice F 756 with the volumes reduced to accommodate nanoparticulate material.

1.4 This test method is part of the in-vitro preclinical characterization and is important for nanoparticulate material that will contact the blood in medical applications.

1.5 The values given in SI units are to be considered as the standard.

1.6 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

PDF Catalog

PDF Pages PDF Title
1 Scope
Referenced Documents
Terminology
Summary of Test Method
Significance and Use
2 Apparatus
Reagents
Preparation of Standards and Controls
TABLE 1
TABLE 2
3 Determination of PFH and TBH in Native Blood Sample
Procedure with the Test Material
FIG. 1
4 Determination of Hemolysis
Calculation
Acceptance Criteria
Report
Precision and Bias
Keywords
X1. RATIONALE
X1.1
ASTM-E2524 2008
$40.63