{"id":279416,"date":"2024-10-19T18:51:19","date_gmt":"2024-10-19T18:51:19","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/bs-en-iso-11137-32017\/"},"modified":"2024-10-25T15:25:17","modified_gmt":"2024-10-25T15:25:17","slug":"bs-en-iso-11137-32017","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/bsi\/bs-en-iso-11137-32017\/","title":{"rendered":"BS EN ISO 11137-3:2017"},"content":{"rendered":"
This document gives guidance on meeting the requirements in ISO 11137\u20111 and ISO 11137\u20112 and in ISO\/TS 13004 relating to dosimetry and its use in development, validation and routine control of a radiation sterilization process.<\/p>\n
PDF Pages<\/th>\n | PDF Title<\/th>\n<\/tr>\n | ||||||
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2<\/td>\n | National foreword <\/td>\n<\/tr>\n | ||||||
4<\/td>\n | European foreword <\/td>\n<\/tr>\n | ||||||
7<\/td>\n | Foreword <\/td>\n<\/tr>\n | ||||||
8<\/td>\n | Introduction <\/td>\n<\/tr>\n | ||||||
9<\/td>\n | 1 Scope 2 Normative references 3 Terms, definitions and symbols 3.1 General <\/td>\n<\/tr>\n | ||||||
11<\/td>\n | 3.2 Symbols <\/td>\n<\/tr>\n | ||||||
12<\/td>\n | 4 Measurement of dose 4.1 General 4.1.1 Direct and indirect dose measurements 4.1.2 Dosimetry systems 4.1.3 Best estimate of dose <\/td>\n<\/tr>\n | ||||||
13<\/td>\n | 4.2 Dosimetry system selection and calibration 4.2.1 General 4.2.2 Selection of dosimetry systems 4.2.3 Calibration of dosimetry systems <\/td>\n<\/tr>\n | ||||||
14<\/td>\n | 4.3 Dose measurement uncertainty 4.3.1 General concepts 4.3.2 The Guide to the expression of uncertainty in measurement (GUM) methodology <\/td>\n<\/tr>\n | ||||||
15<\/td>\n | 4.3.3 Radiation sterilization specific aspects of dose measurement uncertainty <\/td>\n<\/tr>\n | ||||||
16<\/td>\n | 5 Establishing the maximum acceptable dose <\/td>\n<\/tr>\n | ||||||
17<\/td>\n | 6 Establishing the sterilization dose <\/td>\n<\/tr>\n | ||||||
18<\/td>\n | 7 Installation qualification <\/td>\n<\/tr>\n | ||||||
19<\/td>\n | 8 Operational qualification 8.1 General 8.2 Gamma irradiators <\/td>\n<\/tr>\n | ||||||
21<\/td>\n | 8.3 Electron beam irradiators <\/td>\n<\/tr>\n | ||||||
23<\/td>\n | 8.4 X-ray irradiators <\/td>\n<\/tr>\n | ||||||
25<\/td>\n | 9 Performance qualification 9.1 General <\/td>\n<\/tr>\n | ||||||
26<\/td>\n | 9.2 Gamma irradiators 9.2.1 Loading pattern <\/td>\n<\/tr>\n | ||||||
27<\/td>\n | 9.2.2 Dosimetry <\/td>\n<\/tr>\n | ||||||
28<\/td>\n | 9.2.3 Analysis of dose mapping data 9.3 Electron beam irradiators 9.3.1 Loading pattern <\/td>\n<\/tr>\n | ||||||
30<\/td>\n | 9.3.2 Dosimetry 9.3.3 Analysis of dose mapping data <\/td>\n<\/tr>\n | ||||||
31<\/td>\n | 9.4 X-ray irradiators 9.4.1 Loading pattern <\/td>\n<\/tr>\n | ||||||
32<\/td>\n | 9.4.2 Dosimetry <\/td>\n<\/tr>\n | ||||||
33<\/td>\n | 9.4.3 Analysis of dose mapping data 10 Routine monitoring and control 10.1 General <\/td>\n<\/tr>\n | ||||||
34<\/td>\n | 10.2 Frequency of dose measurements <\/td>\n<\/tr>\n | ||||||
35<\/td>\n | Annex A (informative) Mathematical modelling <\/td>\n<\/tr>\n | ||||||
38<\/td>\n | Annex B (informative) Tables of references for dosimetry-related testing during IQ\/OQ\/PQ <\/td>\n<\/tr>\n | ||||||
41<\/td>\n | Annex C (informative) Tolerances associated with doses used in sterilization dose setting\/substantiation in ISO 11137\u20112 and ISO\/TS 13004 <\/td>\n<\/tr>\n | ||||||
42<\/td>\n | Annex D (informative) Application of dose measurement uncertainty in setting process target doses <\/td>\n<\/tr>\n | ||||||
48<\/td>\n | Bibliography <\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":" Sterilization of health care products. Radiation – Guidance on dosimetric aspects of development, validation and routine control<\/b><\/p>\n |